Amyloidosis Symptoms

Amyloidosis Symptoms


Amyloidosis is a rare and serious disease that occurs when a substance called amyloid builds up in your organs. Amyloid is an abnormal protein that is usually produced in your bone marrow and can be deposited in any tissue or organ. The symptoms of amyloidosis can vary widely, depending on where in the body amyloid has accumulated. Understanding these symptoms can help in early detection and treatment of the disease. If you start searching the options below, you can find the best deals for you.

General Symptoms of Amyloidosis

The general symptoms of amyloidosis are often vague and can mimic those of other conditions, making the disease difficult to diagnose. These symptoms can include fatigue, weight loss, and swelling. It’s important to note that these symptoms are not exclusive to amyloidosis and can be caused by a variety of other health conditions.

Fatigue is a common symptom in amyloidosis. This is due to the body’s organs and tissues not functioning optimally due to the presence of amyloid. Weight loss is another common symptom and can occur even when the person’s appetite and diet remain normal. This is often due to the body’s increased metabolic rate as it tries to get rid of the amyloid.

Swelling, particularly in the ankles and legs, is another common symptom of amyloidosis. This is caused by amyloid deposits in the kidneys, which can lead to a condition called nephrotic syndrome. This condition can cause fluid to accumulate in the body, leading to swelling.

Specific Symptoms Based on Organ Involvement

The symptoms of amyloidosis can also vary depending on which organs are affected. The most commonly affected organs are the heart, kidneys, liver, spleen, nervous system, and digestive tract.

Heart Involvement

When amyloid deposits affect the heart, a condition known as cardiac amyloidosis, symptoms can include shortness of breath, irregular heartbeat, and fluid retention. Shortness of breath can occur even during mild activity or at rest, and is often more severe when lying down. Irregular heartbeat can cause feelings of fluttering or skipping beats, while fluid retention can lead to swelling in the legs and ankles.

Cardiac amyloidosis can also cause symptoms such as fatigue, weight loss, and loss of appetite. In some cases, it can lead to serious complications such as heart failure.

Kidney Involvement

Amyloidosis can also affect the kidneys, leading to a condition known as renal amyloidosis. Symptoms can include protein in the urine, swelling in the legs and ankles due to fluid retention, and in severe cases, kidney failure. Protein in the urine, also known as proteinuria, is often the first sign of renal amyloidosis.

As the disease progresses, the kidneys’ ability to filter waste from the blood decreases, leading to kidney failure. This can cause symptoms such as nausea, vomiting, weakness, and shortness of breath.

Nervous System Involvement

When amyloid deposits affect the nervous system, a condition known as peripheral neuropathy can occur. Symptoms can include numbness, tingling, or burning pain in the hands and feet. In some cases, it can also cause weakness and loss of function in the affected areas.

Peripheral neuropathy can also affect the autonomic nervous system, which controls functions such as blood pressure, heart rate, digestion, and sweating. This can lead to symptoms such as dizziness, fainting, diarrhea, constipation, and sexual dysfunction.

Amyloidosis is a complex disease with a wide range of symptoms that can affect various organs in the body. Early detection and treatment are crucial to managing the disease and improving quality of life. If you or a loved one are experiencing any of these symptoms, it’s important to seek medical attention.

Remember, while these symptoms can be indicative of amyloidosis, they can also be caused by a variety of other health conditions. Therefore, it’s important to get a comprehensive evaluation to determine the underlying cause of your symptoms.

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